The pseudoenzyme ADPRHL1 affects cardiac function by regulating the ROCK pathway

Abstract Background Pseudoenzymes, catalytically deficient variants of active enzymes, have a wide range of regulatory functions. ADP-ribosylhydrolase-like 1 (ADPRHL1), a pseudoenzyme belonging to a small group of ADP-ribosylhydrolase enzymes that lacks the amino acid residues necessary for catalyti...

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Main Authors: Lei Tian, Tianwei Guo, Fujian Wu, Rui Bai, Sinan Ai, Hongyue Wang, Yuanxiu Song, Min Zhu, Youxu Jiang, Shuhong Ma, Xiaofeng Zhuang, Shuzhen Guo
格式: 文件
语言:English
出版: BMC 2023-10-01
丛编:Stem Cell Research & Therapy
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在线阅读:https://doi.org/10.1186/s13287-023-03507-0