Investigating PSMA differential expression in canine uroepithelial carcinomas to aid disease-based stratification and guide therapeutic selection

Investigating PSMA differential expression in canine uroepithelial carcinomas to aid disease-based stratification and guide therapeutic selection

Abstract Background In male dogs, uroepithelial cancers include invasive urothelial carcinoma (iUC) and prostate carcinoma (PCA). The inability to distinguish iUC involving the prostate from PCA results in indiscriminate clinical management strategies that could be suboptimal as first-line chemother...

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Bibliographic Details
Main Authors: Matthew R. Berry, Bahaa A. Fadl-Alla, Jonathan Samuelson, Thomas J. Rosol, Timothy M. Fan
Format: Article
Language:English
Published: BMC 2022-12-01
Series:BMC Veterinary Research
Subjects:
Comparative oncology
Canine
Urothelial carcinoma, prostate carcinoma, druggable target
Prostate-specific membrane antigen
Chemotherapy
Online Access:https://doi.org/10.1186/s12917-022-03544-6

Internet

https://doi.org/10.1186/s12917-022-03544-6

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