7-<i>O</i>-methylpunctatin, a Novel Homoisoflavonoid, Inhibits Phenotypic Switch of Human Arteriolar Smooth Muscle Cells

7-<i>O</i>-methylpunctatin, a Novel Homoisoflavonoid, Inhibits Phenotypic Switch of Human Arteriolar Smooth Muscle Cells

Remodeling of arterioles is a pivotal event in the manifestation of many inflammation-based cardio-vasculopathologies, such as hypertension. During these remodeling events, vascular smooth muscle cells (VSMCs) switch from a contractile to a synthetic phenotype. The latter is characterized by increas...

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Bibliographic Details
Main Authors: Manal Fardoun, Rabah Iratni, Hassan Dehaini, Assaad Eid, Tarek Ghaddar, Tamam El-Elimat, Feras Alali, Adnan Badran, Ali H. Eid, Elias Baydoun
Format: Article
Language:English
Published: MDPI AG 2019-11-01
Series:Biomolecules
Subjects:
vascular smooth muscle cells
inflammation
phenotypic switch
homoisoflavonoids
7-o-methylpunctatin
arterioles
Online Access:https://www.mdpi.com/2218-273X/9/11/716

Internet

https://www.mdpi.com/2218-273X/9/11/716

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