Inhibitory effect of protonic bis(5-amino-1,10-phenanthroline) on proliferation of hepatocellular carcinoma and its molecular mechanism

Inhibitory effect of protonic bis(5-amino-1,10-phenanthroline) on proliferation of hepatocellular carcinoma and its molecular mechanism

The incidence of HCC continues to increase rapidly in recent years. the principle of developing anti-HCC drugs is to specifically kill tumor cells, without affecting the function of normal cells. Here we synthesized a novel protonic compound bis(5-amino-1,10-phenanthroline) (P-BAP), and the antitumo...

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Bibliographic Details
Main Authors: Zizhen Zhao, Chen Fu, Yuping Zhang, Yingying Zhang, Xiaoxi Yang, Ailing Fu
Format: Article
Language:English
Published: Elsevier 2022-08-01
Series:Arabian Journal of Chemistry
Subjects:
Hepatocellular carcinoma
Protonic bis-phenanthroline
PLAGL2
Apoptosis
Hydrogen bond
Online Access:http://www.sciencedirect.com/science/article/pii/S1878535222002982

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http://www.sciencedirect.com/science/article/pii/S1878535222002982

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