Novel H2S donor proglumide-ADT-OH protects HUVECs from ox-LDL-induced injury through NF-κB and JAK/SATA pathway

Novel H2S donor proglumide-ADT-OH protects HUVECs from ox-LDL-induced injury through NF-κB and JAK/SATA pathway

As a gaseous mediator, hydrogen sulfide (H2S) has many physiological effects and pathological effects in atherosclerosis. In recent years, many exogenous H2S donors have been synthesized to study atherosclerosis diseases. In this study, proglumide-(5-(4-hydroxyphenyl)-3H-1,2-dithiole-3-thione) (P-A)...

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Bibliographic Details
Main Authors: Ou Xuelan, Xia Tianqin, Yang Chunyan, Yu Chunlei, Zhang Shipeng, Huang Rong, Chen Chuan, Zhou Chunyang
Format: Article
Language:English
Published: De Gruyter 2021-09-01
Series:Open Medicine
Subjects:
hydrogen sulfide donor
atherosclerosis
nf-кb
jak/stat
proglumide-(5-(4-hydroxyphenyl)-3h-1,2-dithiole-3-thione)
Online Access:https://doi.org/10.1515/med-2021-0287

Internet

https://doi.org/10.1515/med-2021-0287

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