Discovery of novel inhibitors of ghrelin O-acyltransferase enzyme: an in-silico approach
Background and purpose: Ghrelin is known as a hunger hormone and plays a pivotal role in appetite, food intake, energy balance, glucose metabolism, and insulin secretion, making it a potential target for the treatment of obesity and type 2 diabetes. The essential maturation step of ghrelin to activa...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Wolters Kluwer Medknow Publications
2022-01-01
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Series: | Research in Pharmaceutical Sciences |
Subjects: | |
Online Access: | http://www.rpsjournal.net/article.asp?issn=1735-5362;year=2022;volume=17;issue=5;spage=540;epage=557;aulast=Hosseini |