Trigonella foenum-graecum seed extract modulates expression of lipid metabolism- related genes in HepG2 cells

Trigonella foenum-graecum seed extract modulates expression of lipid metabolism- related genes in HepG2 cells

Objective: To investigate anti-dyslipidemic effects of hydroalcoholic fenugreek seed extracts, diosgenin, and 4-OH-Ile on HepG2 cell line. Methods: HepG2 cells were treated with hydroalcoholic fenugreek seed extracts, diosgenin, 4-OH-Ile, and orlistat. IC20 was calculated using the MTT method. The c...

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Bibliographic Details
Main Authors: Maryam Mohammad-Sadeghipour, Mehdi Mahmoodi, Soudeh Khanamani Falahati-pour, Alireza Khoshdel, Mohammad Ali Fahmidehkar, Mohammad Reza Mirzaei, Mojgan Noroozi Karimabad, Mohammad Reza Hajizadeh
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2019-01-01
Series:Asian Pacific Journal of Tropical Biomedicine
Subjects:
fenugreek seed extract
diosgenin
4-hydroxy-l-isoleucine
dyslipidemia
obesity
Online Access:http://www.apjtb.org/article.asp?issn=2221-1691;year=2019;volume=9;issue=6;spage=240;epage=248;aulast=Mohammad-Sadeghipour

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http://www.apjtb.org/article.asp?issn=2221-1691;year=2019;volume=9;issue=6;spage=240;epage=248;aulast=Mohammad-Sadeghipour

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