Synthesis of Novel 1-(4-Substituted pyridine-3-sulfonyl)-3-phenylureas with Potential Anticancer Activity

A series of novel 4-substituted-N-(phenylcarbamoyl)-3-pyridinesulfonamides 11–27 have been synthesized by the reaction of 4-substituted pyridine-3-sulfonamides 2–10 with the appropriate aryl isocyanates in presence of potassium carbonate. The in vitro anticancer activity of compounds 11, 12, 14–21 a...

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Bibliographic Details
Main Authors: Krzysztof Szafrański, Jarosław Sławiński
Format: Article
Language:English
Published: MDPI AG 2015-07-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/20/7/12029