Bioenergetic State of Escherichia coli Controls Aminoglycoside Susceptibility

Bioenergetic State of Escherichia coli Controls Aminoglycoside Susceptibility

ABSTRACT Aminoglycosides (AG) have been used against Gram-negative bacteria for decades. Yet, how bacterial metabolism and environmental conditions modify AG toxicity is poorly understood. Here, we show that the level of AG susceptibility varies depending on the nature of the respiratory chain that...

Full description

Bibliographic Details
Main Authors: Jessica Y. El Khoury, Jordi Zamarreño Beas, Allison Huguenot, Béatrice Py, Frédéric Barras
Format: Article
Language:English
Published: American Society for Microbiology 2023-02-01
Series:mBio
Subjects:
Escherichia coli
aminoglycosides
bioenergetics
fumarate respiration
proton motive force
RavA-ViaA
Online Access:https://journals.asm.org/doi/10.1128/mbio.03302-22

Internet

https://journals.asm.org/doi/10.1128/mbio.03302-22

Similar Items