Experimental evolution of diverse Escherichia coli metabolic mutants identifies genetic loci for convergent adaptation of growth rate.

Cell growth is determined by substrate availability and the cell's metabolic capacity to assimilate substrates into building blocks. Metabolic genes that determine growth rate may interact synergistically or antagonistically, and can accelerate or slow growth, depending on genetic background an...

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Bibliographic Details
Main Authors: Thomas P Wytock, Aretha Fiebig, Jonathan W Willett, Julien Herrou, Aleksandra Fergin, Adilson E Motter, Sean Crosson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-03-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC5892946?pdf=render