The insulin-like growth factor system in chronic kidney disease: Pathophysiology and therapeutic opportunities
The growth hormone–insulin-like growth factor–insulin-like growth factor binding protein (GH–IGF–IGFBP) axis plays a critical role in the maintenance of normal renal function and the pathogenesis and progression of chronic kidney disease (CKD). Serum IGF-I and IGFBPs are altered with different stage...
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Format: | Article |
Language: | English |
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The Korean Society of Nephrology
2012-03-01
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Series: | Kidney Research and Clinical Practice |
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Online Access: | http://www.sciencedirect.com/science/article/pii/S2211913211000064 |