Evaluation of Confocal Fluorescence Spectroscopy for the Detection of Pathological Prion Proteins

Prion diseases or transmissible spongiform encephalopathies (TSEs) are characterized by the accumulation in the brain of PrPSc, an abnormal isoform of the host-encoded glycoprotein PrPC. PrPSc is a reliable marker for the post mortem diagnosis of TSEs but its use as a marker for a pre-clin...

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Bibliographic Details
Main Authors: Anja Dietrich, Karin Bossart, Bruno Oesch, Christoph Stamm, Alex J. Raeber
Format: Article
Language:deu
Published: Swiss Chemical Society 2005-05-01
Series:CHIMIA
Subjects:
Online Access:https://chimia.ch/chimia/article/view/3981