Noise-driven stem cell and progenitor population dynamics.

The balance between maintenance of the stem cell state and terminal differentiation is influenced by the cellular environment. The switching between these states has long been understood as a transition between attractor states of a molecular network. Herein, stochastic fluctuations are either suppr...

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Bibliographic Details
Main Authors: Martin Hoffmann, Hannah H Chang, Sui Huang, Donald E Ingber, Markus Loeffler, Joerg Galle
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-08-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2488392?pdf=render