Enaminones as Building Blocks for the Synthesis of Substituted Pyrazoles with Antitumor and Antimicrobial Activities
Novel N-arylpyrazole-containing enaminones 2a,b were synthesized as key intermediates. Reactions of 2a,b with active methylene compounds in acetic acid in the presence of ammonium acetate afforded substituted pyridine derivatives 5a-d. Enaminones 2a,b also reacted with aliphatic amines such as hydra...
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| Format: | Article |
| Language: | English |
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MDPI AG
2011-02-01
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| Series: | Molecules |
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| Online Access: | http://www.mdpi.com/1420-3049/16/2/1834/ |