Pathway-Based Analysis Revealed the Role of Keap1-Nrf2 Pathway and PI3K-Akt Pathway in Chinese Esophageal Squamous Cell Carcinoma Patients With Definitive Chemoradiotherapy

Pathway-Based Analysis Revealed the Role of Keap1-Nrf2 Pathway and PI3K-Akt Pathway in Chinese Esophageal Squamous Cell Carcinoma Patients With Definitive Chemoradiotherapy

Esophageal squamous cell carcinoma (ESCC) is the major type of EC in China. Chemoradiotherapy is a standard definitive treatment for early-stage EC and significantly improves local control and overall survival for late-stage patients. However, chemoradiotherapy resistance, which limits therapeutic e...

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Bibliographic Details
Main Authors: Honghai Dai, Yanjun Wei, Yunxia Liu, Jingwen Liu, Ruoying Yu, Junli Zhang, Jiaohui Pang, Yang Shao, Qiang Li, Zhe Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Genetics
Subjects:
ESCC (Esophageal squamous cell carcinoma)
Keap1-Nrf2 pathway
PI3K-Akt pathway
chemoradiotherapy
pathway-based analysis
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2021.799663/full

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https://www.frontiersin.org/articles/10.3389/fgene.2021.799663/full

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