Anti-CD40 mAb enhanced efficacy of anti-PD1 against osteosarcoma

The overall survival rate of patients with osteosarcoma has remained stagnant at 15–30% for several decades. Although immunotherapy has revolutionized the oncology field, largely attributed to the success of immune-checkpoint blockade, the durability and efficacy of anti-PD1 (programmed cell death p...

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Bibliographic Details
Main Authors: Jingzhe Zhang, Ye Li, Shoujun Yang, Lening Zhang, Wenjun Wang
Format: Article
Language:English
Published: Elsevier 2019-08-01
Series:Journal of Bone Oncology
Online Access:http://www.sciencedirect.com/science/article/pii/S2212137419300661