Anti-CD40 mAb enhanced efficacy of anti-PD1 against osteosarcoma
The overall survival rate of patients with osteosarcoma has remained stagnant at 15–30% for several decades. Although immunotherapy has revolutionized the oncology field, largely attributed to the success of immune-checkpoint blockade, the durability and efficacy of anti-PD1 (programmed cell death p...
Main Authors: | Jingzhe Zhang, Ye Li, Shoujun Yang, Lening Zhang, Wenjun Wang |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2019-08-01
|
Series: | Journal of Bone Oncology |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2212137419300661 |
Similar Items
-
Comparative efficacy and safety of chimeric and recombinant anti-TNF-α mAbs
by: V. N. Drozdov, et al.
Published: (2021-05-01) -
Construction and characterization of an anti-CD20 mAb nanocomb with exceptionally excellent lymphoma-suppressing activity
by: Li H, et al.
Published: (2015-07-01) -
Immuno-PET Imaging of Atherosclerotic Plaques with [<sup>89</sup>Zr]Zr-Anti-CD40 mAb—Proof of Concept
by: Kikkie Poels, et al.
Published: (2022-03-01) -
New Insights on the Role of Anti-PD-L1 and Anti-CTLA-4 mAbs on Different Lymphocytes Subpopulations in TNBC
by: Rosa Rapuano Lembo, et al.
Published: (2022-10-01) -
Anti-PD-1 Monoclonal Antibodies (mAbs) Are Superior to Anti-PD-L1 mAbs When Combined with Chemotherapy in First-Line Treatment for Metastatic Non-Small Cell Lung Cancer (mNSCLC): A Network Meta-Analysis
by: Joe Q. Wei, et al.
Published: (2023-06-01)