FBXW7 circular RNA regulates proliferation, migration and invasion of colorectal carcinoma through NEK2, mTOR, and PTEN signaling pathways in vitro and in vivo

FBXW7 circular RNA regulates proliferation, migration and invasion of colorectal carcinoma through NEK2, mTOR, and PTEN signaling pathways in vitro and in vivo

Abstract Backgrounds A number of circular RNAs (circRNAs) have been identified in various cancer including F-box and WD repeat domain containing 7 (FBXW7) circular RNA (circ-FBXW7), which can suppress glioma cell growth. However, the role of circ-FBXW7 in colorectal cancer (CRC) remains unclear. We...

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Bibliographic Details
Main Authors: Haoran Lu, Baofu Yao, Xinyuan Wen, Baoqing Jia
Format: Article
Language:English
Published: BMC 2019-09-01
Series:BMC Cancer
Subjects:
Colorectal cancer
circRNAs
Circ-FBXW7
Cell proliferation
Migration
Invasion
Online Access:http://link.springer.com/article/10.1186/s12885-019-6028-z

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http://link.springer.com/article/10.1186/s12885-019-6028-z

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