New Amino Acid Schiff Bases as Anticancer Agents via Potential Mitochondrial Complex I-Associated Hexokinase Inhibition and Targeting AMP-Protein Kinases/mTOR Signaling Pathway

Two series of novel amino acid Schiff base ligands containing heterocyclic moieties, such as quinazolinone <b>3</b>–<b>11</b> and indole <b>12</b>–<b>20</b> were successfully synthesized and confirmed by spectroscopic techniques and elemental analysis....

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Bibliographic Details
Main Authors: Ahmed A. Noser, Aboubakr H. Abdelmonsef, Mohamed El-Naggar, Maha M. Salem
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/26/17/5332