Inhibitors of Arg-Gly-Asp-Binding Integrins Reduce Development of Pancreatic Fibrosis in MiceSummary

Inhibitors of Arg-Gly-Asp-Binding Integrins Reduce Development of Pancreatic Fibrosis in MiceSummary

Background & Aims: Pancreatic stellate cells (PSCs) regulate the development of chronic pancreatitis (CP) and are activated by the cytokine transforming growth factor β (TGFB). Integrins of the αv family promote TGFB signaling in mice, probably by interacting with the Arg-Gly-Asp (RGD) sequenc...

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Bibliographic Details
Main Authors: Barbara Ulmasov, Brent A. Neuschwander-Tetri, Jinping Lai, Vladimir Monastyrskiy, Trisha Bhat, Matthew P. Yates, Jonathan Oliva, Michael J. Prinsen, Peter G. Ruminski, David W. Griggs
Format: Article
Language:English
Published: Elsevier 2016-07-01
Series:Cellular and Molecular Gastroenterology and Hepatology
Online Access:http://www.sciencedirect.com/science/article/pii/S2352345X1630008X

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http://www.sciencedirect.com/science/article/pii/S2352345X1630008X

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