Feasibility of using 454 pyrosequencing for studying quasispecies of the whole dengue viral genome

<p>Abstract</p> <p>Background</p> <p>Dengue is the world's most common mosquito-borne viral disease. Poor proofreading by RNA polymerase during its replication results in the accumulation of mutations in its genome. This leads to a diversity of genotypes in the vir...

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Main Authors: Chin-inmanu Kwanrutai, Suttitheptumrong Aroonroong, Sangsrakru Duangjai, Tangphatsornruang Sithichoke, Tragoonrung Somvong, Malasit Prida, Tungpradabkul Sumalee, Suriyaphol Prapat
Format: Article
Language:English
Published: BMC 2012-12-01
Series:BMC Genomics