Feasibility of using 454 pyrosequencing for studying quasispecies of the whole dengue viral genome
<p>Abstract</p> <p>Background</p> <p>Dengue is the world's most common mosquito-borne viral disease. Poor proofreading by RNA polymerase during its replication results in the accumulation of mutations in its genome. This leads to a diversity of genotypes in the vir...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2012-12-01
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Series: | BMC Genomics |