Oxidative 1,2-carboamination of alkenes with alkyl nitriles and amines toward γ-amino alkyl nitriles
Difunctionalization of readily available alkenes is a powerful method to quickly build molecular complexity. Here the authors report a three-component, oxidative carboamination between alkenes, alkyl nitriles and amines, producingγ-amino alkyl nitriles.
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2017-04-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/ncomms14720 |