NEU1 and NEU3 enzymes alter CD22 organization on B cells

The B cell membrane expresses sialic-acid-binding immunoglobulin-like lectins, also called Siglecs, that are important for modulating immune response. Siglecs have interactions with sialoglycoproteins found on the same membrane (cis-ligands) that result in homotypic and heterotypic receptor clusters...

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Bibliographic Details
Main Authors: Hanh-Thuc Ton Tran, Caishun Li, Radhika Chakraberty, Christopher W. Cairo
Format: Article
Language:English
Published: Elsevier 2022-09-01
Series:Biophysical Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2667074722000210