Primary Human Trophoblasts Mimic the Preeclampsia Phenotype after Acute Hypoxia–Reoxygenation Insult

Primary Human Trophoblasts Mimic the Preeclampsia Phenotype after Acute Hypoxia–Reoxygenation Insult

Preeclampsia (PE) is a pregnancy-specific disorder that affects 3 to 5% of pregnancies worldwide and is one of the leading causes of maternal and fetal morbidity and mortality. Nevertheless, how these events occur remains unclear. We hypothesized that the induction of hypoxic conditions in vitro in...

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Bibliographic Details
Main Authors: Barbara Fuenzalida, Sampada Kallol, Jonas Zaugg, Martin Mueller, Hiten D. Mistry, Jaime Gutierrez, Andrea Leiva, Christiane Albrecht
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Cells
Subjects:
preeclampsia
hypoxia
hypoxia/reoxygenation
sFlT-1/PlGF ratio
primary trophoblast
inflammation
Online Access:https://www.mdpi.com/2073-4409/11/12/1898

Internet

https://www.mdpi.com/2073-4409/11/12/1898

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