UFL1, a UFMylation E3 ligase, plays a crucial role in multiple cellular stress responses

UFL1, a UFMylation E3 ligase, plays a crucial role in multiple cellular stress responses

The UFM1 conjugation system(UFMylation)is a novel type of ubiquitin-like system that plays an indispensable role in maintaining cell homeostasis under various cellular stress. Similar to ubiquitination, UFMylation consists of a three-step enzymatic reaction with E1-like enzymes ubiquitin-like modifi...

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Bibliographic Details
Main Authors: Qiang Jiang, Yongsheng Wang, Minghui Xiang, Jiamin Hua, Tianci Zhou, Fanghui Chen, Xiaoyang Lv, Jinming Huang, Yafei Cai
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Endocrinology
Subjects:
UFL1
Ufmylation modification
ER stress
genotoxic stress
oncogenic stress
inflammation
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2023.1123124/full

Internet

https://www.frontiersin.org/articles/10.3389/fendo.2023.1123124/full

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