Dihydrotanshinone I protects human chondrocytes and alleviates damage from spontaneous osteoarthritis in a guinea pig model

Abstract Osteoarthritis (OA) is the most common degenerative joint disease. Currently, no satisfactory pharmacological treatment exists for OA. The potential anti-inflammatory properties of Dihydrotanshinone I (DHT) have been reported, but its effects on OA are unclear. In this study, we assess the...

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Bibliographic Details
Main Authors: Yan-Zhuo Zhang, Zhen-Jie Wei, Shu-Nan Yu, Xin-Yu Wang, Ying Wang, Cheng-Ai Wu, Xu Jiang
Format: Article
Language:English
Published: Nature Portfolio 2023-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-48902-y