Acute promyelocytic leukemia: the study of t(15;17) translocation by fluorescent in situ hybridization, reverse transcriptase-polymerase chain reaction and cytogenetic techniques

Acute promyelocytic leukemia: the study of t(15;17) translocation by fluorescent in situ hybridization, reverse transcriptase-polymerase chain reaction and cytogenetic techniques

Acute promyelocytic leukemia (AML M3) is a well-defined subtype of leukemia with specific and peculiar characteristics. Immediate identification of t(15;17) or the PML/RARA gene rearrangement is fundamental for treatment. The objective of the present study was to compare fluorescent in situ hybridiz...

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Bibliographic Details
Main Authors: M.L.L.F. Chauffaille, M.S. Figueiredo, R. Beltrani, S.V. Antunes, M. Yamamoto, J. Kerbauy
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2001-06-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
acute promyelocytic leukemia
karyotype
FISH
RT-PCR
PML/RARA genem rearrangement
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2001000600006

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2001000600006

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