Plasmodium vivax tryptophan-rich antigen reduces type I collagen secretion via the NF-κBp65 pathway in splenic fibroblasts

Plasmodium vivax tryptophan-rich antigen reduces type I collagen secretion via the NF-κBp65 pathway in splenic fibroblasts

Abstract Background The spleen plays a critical role in the immune response against malaria parasite infection, where splenic fibroblasts (SFs) are abundantly present and contribute to immune function by secreting type I collagen (collagen I). The protein family is characterized by Plasmodium vivax...

Full description

Bibliographic Details
Main Authors: Wei-Zhong Kong, Hang-Ye Zhang, Yi-Fan Sun, Jing Song, Jian Jiang, Heng-Yuan Cui, Yu Zhang, Su Han, Yang Cheng
Format: Article
Language:English
Published: BMC 2024-05-01
Series:Parasites & Vectors
Subjects:
Plasmodium vivax
PvTRAgs
Spleen fibroblasts
NF-κBp65 pathway
Collagen
Online Access:https://doi.org/10.1186/s13071-024-06264-y

Internet

https://doi.org/10.1186/s13071-024-06264-y

Similar Items