Prefrontal Glutamate Neurotransmission in PTSD: A Novel Approach to Estimate Synaptic Strength in Vivo in Humans

Prefrontal Glutamate Neurotransmission in PTSD: A Novel Approach to Estimate Synaptic Strength in Vivo in Humans

Background Trauma and chronic stress are believed to induce and exacerbate psychopathology by disrupting glutamate synaptic strength. However, in vivo in human methods to estimate synaptic strength are limited. In this study, we established a novel putative biomarker of glutamatergic synaptic streng...

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Bibliographic Details
Main Authors: Lynnette A. Averill, Lihong Jiang, Prerana Purohit, Anastasia Coppoli, Christopher L. Averill, Jeremy Roscoe, Benjamin Kelmendi, Henk M. De Feyter, Robin A de Graaf, Ralitza Gueorguieva, Gerard Sanacora, John H. Krystal, Douglas L. Rothman, Graeme F. Mason, Chadi G. Abdallah
Format: Article
Language:English
Published: SAGE Publishing 2022-04-01
Series:Chronic Stress
Online Access:https://doi.org/10.1177/24705470221092734

Internet

https://doi.org/10.1177/24705470221092734

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