Dopamine D2 receptor antagonist counteracts hyperglycemia and insulin resistance in diet-induced obese male mice.

Dopamine D2 receptor antagonist counteracts hyperglycemia and insulin resistance in diet-induced obese male mice.

Obesity leads to insulin resistance (IR) and type 2 diabetes. In humans, low levels of the hormone prolactin (PRL) correlate with IR, adipose tissue (AT) dysfunction, and increased prevalence of T2D. In obese rats, PRL treatment promotes insulin sensitivity and reduces visceral AT adipocyte hypertro...

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Xehetasun bibliografikoak
Egile Nagusiak: Dina I Vázquez-Carrillo, Ana Luisa Ocampo-Ruiz, Arelí Báez-Meza, Gabriela Ramírez-Hernández, Elva Adán-Castro, José Fernando García-Rodrigo, José Luis Dena-Beltrán, Ericka A de Los Ríos, Magdalena Karina Sánchez-Martínez, María Georgina Ortiz, Gonzalo Martínez de la Escalera, Carmen Clapp, Yazmín Macotela
Formatua: Artikulua
Hizkuntza:English
Argitaratua: Public Library of Science (PLoS) 2024-01-01
Saila:PLoS ONE
Sarrera elektronikoa:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0301496&type=printable

Internet

https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0301496&type=printable

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