Screening of Manilkara zapota (L) P. Royen stem bark ethanolic extract for in vitro α-glucosidase inhibition, preliminary antidiabetic effects, and improvement of diabetes and its complications in alloxan-induced diabetes in Wistar rats

Screening of Manilkara zapota (L) P. Royen stem bark ethanolic extract for in vitro α-glucosidase inhibition, preliminary antidiabetic effects, and improvement of diabetes and its complications in alloxan-induced diabetes in Wistar rats

Abstract Background A perusal of the literature suggested that Manilkara zapota (L.) P. Royen stem bark (MZSB) is enriched with several bioactive phytoconstituents but had not been yet screened for its in vitro and in vivo antidiabetic potentials. Thus, the present study aimed to investigate the eff...

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Bibliographic Details
Main Authors: Pravin P. Karle, Shashikant C. Dhawale, Rajesh J. Mandade, Vijay V. Navghare
Format: Article
Language:English
Published: SpringerOpen 2022-04-01
Series:Bulletin of the National Research Centre
Subjects:
Diabetes mellitus
α-Glucosidase enzyme inhibition
Blood glucose
Serum lipids
Cardiovascular risk indices
Diabetic nephropathies
Online Access:https://doi.org/10.1186/s42269-022-00783-3

Internet

https://doi.org/10.1186/s42269-022-00783-3

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