Replication of linkage of familial hypobetalipoproteinemia to chromosome 3p in six kindreds

Replication of linkage of familial hypobetalipoproteinemia to chromosome 3p in six kindreds

Familial hypobetalipoproteinemia (FHBL) is a genetically heterogeneous condition characterized by very low apolipoprotein B (apoB) concentrations in plasma and/or low levels of LDL-cholesterol (LDL-C) with a propensity to developing fatty liver. In a minority of cases, truncation-specifying mutation...

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Bibliographic Details
Main Authors: Rosalind J. Neuman, Bo Yuan, Daniela S. Gerhard, Kuang-Yu Liu, Pin Yue, Shenghui Duan, Maurizio Averna, Gustav Schonfeld
Format: Article
Language:English
Published: Elsevier 2002-03-01
Series:Journal of Lipid Research
Subjects:
linkage analysis
genetic
Markov chain Monte Carlo
variance components
oligogenic
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520301474

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http://www.sciencedirect.com/science/article/pii/S0022227520301474

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