A trade-off between the fitness cost of functional integrases and long-term stability of integrons.

Horizontal gene transfer (HGT) plays a major role in bacterial microevolution as evident from the rapid emergence and spread of antimicrobial drug resistance. Few studies have however addressed the population dynamics of newly imported genetic elements after HGT. Here, we show that newly acquired cl...

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Bibliographic Details
Main Authors: Irina Starikova, Klaus Harms, Pål Haugen, Tracy T M Lunde, Raul Primicerio, Ørjan Samuelsen, Kaare M Nielsen, Pål J Johnsen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Pathogens
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23209414/?tool=EBI