Distinct single amino acid replacements in the control of virulence regulator protein differentially impact streptococcal pathogenesis.

Distinct single amino acid replacements in the control of virulence regulator protein differentially impact streptococcal pathogenesis.

Sequencing of invasive strains of group A streptococci (GAS) has revealed a diverse array of single nucleotide polymorphisms in the gene encoding the control of virulence regulator (CovR) protein. However, there is limited information regarding the molecular mechanisms by which CovR single amino aci...

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Bibliographic Details
Main Authors: Nicola Horstmann, Pranoti Sahasrabhojane, Bryce Suber, Muthiah Kumaraswami, Randall J Olsen, Anthony Flores, James M Musser, Richard G Brennan, Samuel A Shelburne
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-10-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3197619?pdf=render

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http://europepmc.org/articles/PMC3197619?pdf=render

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