The effect of Nrf2 pathway activation on human pancreatic islet cells.

The effect of Nrf2 pathway activation on human pancreatic islet cells.

Pancreatic islets are known to contain low level of antioxidants that renders them vulnerable to oxidative stress. Nrf2 is the master regulator of numerous genes, encoding antioxidant, detoxifying, and cytoprotective molecules. Activation of Nrf2 pathway induces up-regulation of numerous genes encod...

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Bibliographic Details
Main Authors: Yuichi Masuda, Nosratola D Vaziri, Shiri Li, Aimee Le, Mohammad Hajighasemi-Ossareh, Lourdes Robles, Clarence E Foster, Michael J Stamos, Ismail Al-Abodullah, Camillo Ricordi, Hirohito Ichii
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4482439?pdf=render

Internet

http://europepmc.org/articles/PMC4482439?pdf=render

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