Kinugasa Reactions in Water: From Green Chemistry to Bioorthogonal Labelling

The Kinugasa reaction has become an efficient method for the direct synthesis of β-lactams from substituted nitrones and copper(I) acetylides. In recent years, the reaction scope has been expanded to include the use of water as the solvent, and with micelle-promoted [3+2] cycloadditions followed by...

Full description

Bibliographic Details
Main Authors: Mariya Chigrinova, Douglas A. MacKenzie, Allison R. Sherratt, Lawrence L. W. Cheung, John Paul Pezacki
Format: Article
Language:English
Published: MDPI AG 2015-04-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/20/4/6959