VEGFR-2 reduces while combined VEGFR-2 and -3 signaling increases inflammation in apical periodontitis

Background: In apical periodontitis, oral pathogens provoke an inflammatory response in the apical area that induces bone resorptive lesions. In inflammation, angio- and lymphangiogenesis take place. Vascular endothelial growth factors (VEGFs) and their receptors (VEGFRs) are key players in these pr...

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Bibliographic Details
Main Authors: Anca Virtej, Panagiota Papadakou, Hajime Sasaki, Athanasia Bletsa, Ellen Berggreen
Format: Article
Language:English
Published: Taylor & Francis Group 2016-09-01
Series:Journal of Oral Microbiology
Subjects:
Online Access:http://www.journaloforalmicrobiology.net/index.php/jom/article/view/32433/48779