Chimeric Oncolytic Adenovirus Armed Chemokine Rantes for Treatment of Breast Cancer

Chimeric Oncolytic Adenovirus Armed Chemokine Rantes for Treatment of Breast Cancer

The immunosuppressive state in the tumor microenvironment (TME) of breast cancer makes it difficult to treat with immunotherapy. Oncolytic viruses not only lyse tumor cells but also reshape the TME. Therefore, they can play a multi-mechanism synergistic effect with immunotherapy. In this study, an o...

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Bibliographic Details
Main Authors: Lin Ang, Jiang Li, Hui Dong, Chunhong Wang, Jin Huang, Mingcong Li, Min Zhao, Changqing Su, Qiang Wu
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Bioengineering
Subjects:
triple negative breast cancer
tumor microenvironment
oncolytic adenovirus
chemokine
immunotherapy
Online Access:https://www.mdpi.com/2306-5354/9/8/342

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https://www.mdpi.com/2306-5354/9/8/342

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