Reverse Nearest Neighbor Search on a Protein-Protein Interaction Network to Infer Protein-Disease Associations

The associations between proteins and diseases are crucial information for investigating pathological mechanisms. However, the number of known and reliable protein-disease associations is quite small. In this study, an analysis framework to infer associations between proteins and diseases was develo...

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Bibliographic Details
Main Authors: Apichat Suratanee, Kitiporn Plaimas
Format: Article
Language:English
Published: SAGE Publishing 2017-07-01
Series:Bioinformatics and Biology Insights
Online Access:https://doi.org/10.1177/1177932217720405