The Spatiotemporal Control of Zygotic Genome Activation

Summary: One of the earliest and most significant events in embryonic development is zygotic genome activation (ZGA). In several species, bulk transcription begins at the midblastula transition (MBT) when, after a certain number of cleavages, the embryo attains a particular nuclear-to-cytoplasmic (N...

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Bibliographic Details
Main Authors: George E. Gentsch, Nick D.L. Owens, James C. Smith
Format: Article
Language:English
Published: Elsevier 2019-06-01
Series:iScience
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004219301956