TMEFF2 is a PDGF-AA binding protein with methylation-associated gene silencing in multiple cancer types including glioma.

BACKGROUND: TMEFF2 is a protein containing a single EGF-like domain and two follistatin-like modules. The biological function of TMEFF2 remains unclear with conflicting reports suggesting both a positive and a negative association between TMEFF2 expression and human cancers. METHODOLOGY/PRINCIPAL FI...

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Bibliographic Details
Main Authors: Kui Lin, James R Taylor, Thomas D Wu, Johnny Gutierrez, J Michael Elliott, Jean-Michel Vernes, Hartmut Koeppen, Heidi S Phillips, Frederic J de Sauvage, Y Gloria Meng
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3084709?pdf=render