Adult human cardiac stem cell supplementation effectively increases contractile function and maturation in human engineered cardiac tissues

Adult human cardiac stem cell supplementation effectively increases contractile function and maturation in human engineered cardiac tissues

Abstract Background Delivery of stem cells to the failing heart is a promising therapeutic strategy. However, the improvement in cardiac function in animal studies has not fully translated to humans. To help bridge the gap between species, we investigated the effects of adult human cardiac stem cell...

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Detalhes bibliográficos
Principais autores: Jack F. Murphy, Joshua Mayourian, Francesca Stillitano, Sadek Munawar, Kathleen M. Broughton, Esperanza Agullo-Pascual, Mark A. Sussman, Roger J. Hajjar, Kevin D. Costa, Irene C. Turnbull
Formato: Artigo
Idioma:English
Publicado em: BMC 2019-12-01
coleção:Stem Cell Research & Therapy
Assuntos:
Human cardiac stem cells
Human engineered cardiac tissue
Contractility
Myocardial function
Cardiomyocyte maturation
Acesso em linha:https://doi.org/10.1186/s13287-019-1486-4

Internet

https://doi.org/10.1186/s13287-019-1486-4

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