Acidified bile acids enhance tumor progression and telomerase activity of gastric cancer in mice dependent on c‐Myc expression

Acidified bile acids enhance tumor progression and telomerase activity of gastric cancer in mice dependent on c‐Myc expression

Abstract c‐Myc overexpression has been implicated in several malignancies including gastric cancer. Here, we report that acidified bile acids enhance tumor progression and telomerase activity in gastric cancer via c‐Myc activation both in vivo and in vitro. c‐Myc mRNA and protein levels were assesse...

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Bibliographic Details
Main Authors: Xiaolong Wang, Lei Sun, Xijing Wang, Huafeng Kang, Xiaobin Ma, Meng Wang, Shuai Lin, Meng Liu, Cong Dai, Zhijun Dai
Format: Article
Language:English
Published: Wiley 2017-04-01
Series:Cancer Medicine
Subjects:
Acidified bile acids
c‐Myc activation
duodenal reflux
gastric cancer
telomerase activity
Online Access:https://doi.org/10.1002/cam4.999

Internet

https://doi.org/10.1002/cam4.999

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