Hsp40/JDP Requirements for the Propagation of Synthetic Yeast Prions

Hsp40/JDP Requirements for the Propagation of Synthetic Yeast Prions

Yeast prions are protein-based transmissible elements, most of which are amyloids. The chaperone protein network in yeast is inexorably linked to the spreading of prions during cell division by fragmentation of amyloid prion aggregates. Specifically, the core “prion fragmentation machinery” includes...

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Bibliographic Details
Main Authors: Sarah C. Miller, Andrea K. Wegrzynowicz, Sierra J. Cole, Rachel E. Hayward, Samantha J. Ganser, Justin K. Hines
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Viruses
Subjects:
J-domain protein
Hsp40
Sis1
yeast prion
molecular chaperone
amyloid
Online Access:https://www.mdpi.com/1999-4915/14/10/2160

Internet

https://www.mdpi.com/1999-4915/14/10/2160

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