Examination of the Role of Mitochondrial Morphology and Function in the Cardioprotective Effect of Sodium Nitrite Administered 24 h Before Ischemia/Reperfusion Injury

Examination of the Role of Mitochondrial Morphology and Function in the Cardioprotective Effect of Sodium Nitrite Administered 24 h Before Ischemia/Reperfusion Injury

Background: We have previous evidence that in anesthetized dogs the inorganic sodium nitrite protects against the severe ventricular arrhythmias, resulting from coronary artery occlusion and reperfusion, when administered 24 h before. The present study aimed to examine, whether in this effect change...

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Bibliographic Details
Main Authors: Vivien Demeter-Haludka, Mária Kovács, Alexandra Petrus, Roland Patai, Danina M. Muntean, László Siklós, Ágnes Végh
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-03-01
Series:Frontiers in Pharmacology
Subjects:
ischaemia/reperfusion
arrhythmia
sodium nitrite
cardioprotection
mitochondrial structure
mitochondrial respiration
Online Access:http://journal.frontiersin.org/article/10.3389/fphar.2018.00286/full

Internet

http://journal.frontiersin.org/article/10.3389/fphar.2018.00286/full

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