Tissue-specific features of mitochondrial DNA polymorphisms

Mitochondrial DNA (mtDNA) has a polyploid structure, i.e. every cell contains thousands of mtDNA copies. However, in view of heredity or somatic mutations, mtDNA copies vary from one another (heteroplasmy). Moreover, heteroplasmy may occur at both the intracellular, intercellular, or even intertissu...

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Bibliographic Details
Main Authors: N. A. Litvinova, A. S. Voronkova, E. A. Nikolaeva, V. S. Sukhorukov
Format: Article
Language:Russian
Published: Ltd. “The National Academy of Pediatric Science and Innovation” 2016-03-01
Series:Rossijskij Vestnik Perinatologii i Pediatrii
Subjects:
Online Access:https://www.ped-perinatology.ru/jour/article/view/159