Optogenetic manipulation of cardiac repolarization gradients using sub-threshold illumination
Introduction: Mechanisms underlying cardiac arrhythmias are typically driven by abnormalities in cardiac conduction and/or heterogeneities in repolarization time (RT) across the heart. While conduction slowing can be caused by either electrophysiological defects or physical blockade in cardiac tissu...
Main Authors: | Gerard A. Marchal, Valentina Biasci, Leslie M. Loew, Annibale Biggeri, Marina Campione, Leonardo Sacconi |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2023-05-01
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Series: | Frontiers in Physiology |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fphys.2023.1167524/full |
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