Microwave-Assisted Freeze–Drying: Impact of Microwave Radiation on the Quality of High-Concentration Antibody Formulations

Microwave-Assisted Freeze–Drying: Impact of Microwave Radiation on the Quality of High-Concentration Antibody Formulations

Microwave-assisted freeze-drying (MFD) offers significant time savings compared to conventional freeze-drying (CFD). While a few studies have investigated the stability of biopharmaceuticals with low protein concentrations after MFD and storage, the impact of MFD on high-concentration monoclonal ant...

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Bibliographic Details
Main Authors: Nicole Härdter, Raimund Geidobler, Ingo Presser, Gerhard Winter
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:Pharmaceutics
Subjects:
freeze-drying
lyophilization
microwave
protein
monoclonal antibody
stability
Online Access:https://www.mdpi.com/1999-4923/15/12/2783

Internet

https://www.mdpi.com/1999-4923/15/12/2783

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