<it>KRAS </it>analysis in colorectal carcinoma: Analytical aspects of Pyrosequencing and allele-specific PCR in clinical practice

<p>Abstract</p> <p>Background</p> <p>Epidermal growth factor receptor inhibitor therapy is now approved for treatment of metastatic colorectal carcinomas (CRC) in patients with tumors lacking <it>KRAS </it>mutations. Several procedures to detect <it>KR...

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Bibliographic Details
Main Authors: Birgisson Helgi, Glimelius Bengt, Lindell Monica, Edlund Karolina, Sundström Magnus, Micke Patrick, Botling Johan
Format: Article
Language:English
Published: BMC 2010-12-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/10/660