Maternal diabetes-mediated RORA suppression contributes to gastrointestinal symptoms in autism-like mouse offspring

Maternal diabetes-mediated RORA suppression contributes to gastrointestinal symptoms in autism-like mouse offspring

Abstract Background Retinoic acid-related orphan receptor alpha (RORA) has been reported to be suppressed in autistic patients and is associated with autism spectrum disorders (ASD), although the potential role and mechanism of RORA on gastrointestinal (GI) symptoms in ASD patients is still not repo...

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Bibliographic Details
Main Authors: Li Xiao, Min Wang, Wanhua Zhang, Yuan Song, Jiaying Zeng, Huilin Li, Hong Yu, Ling Li, Pingming Gao, Paul Yao
Format: Article
Language:English
Published: BMC 2022-02-01
Series:BMC Neuroscience
Subjects:
Autism
Gastrointestinal symptoms
Inflammation
Maternal diabetes
Oxidative stress
RORA
Online Access:https://doi.org/10.1186/s12868-022-00693-0

Internet

https://doi.org/10.1186/s12868-022-00693-0

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